The RIMS community mourns the loss of Professor Giancarlo Comi, a visionary neurologist and pioneer in the field of multiple sclerosis research, President of the European Charcot Foundation. A pioneer in proposing early treatment of multiple sclerosis, his groundbreaking contributions extended beyond pharmacological advances, shedding light on the biological effects of rehabilitation in multiple sclerosis. With his strong support to the PROMS initiative, he was a great advocate of people living with the disease towards their active contribution to MS research and care.

Professor Comi's work emphasized the critical role of rehabilitation in modulating neuroplasticity and improving patient outcomes. We honor his legacy and enduring impact on science, medicine, and the lives of those with MS worldwide.